Area: Biology and Genetics

Article Index


University of Vienna - Faculty of Sport Science
Auf der Schmelz 6, 1150 Wien, Austria

Tel +43 14277.48871 - Fax +43 14277.48869 - This email address is being protected from spambots. You need JavaScript enabled to view it.

Wessner BarbaraMolecular biologist with a strong background in nutritional science and immunology. Previously, Research Associate and lecturer at the Medical University of Vienna (1999-2006), now entrusted with the task to establish and manage a molecular biology laboratory at the Department of Sports and Exercise Physiology located at the Institute of Sports Sciences at the University of Vienna which aims to study molecular, cellular, physiological and integrative processes of normal and altered skeletal muscle during health, ageing and disease. Main research topics include the influence of nutritive antioxidants on the cellular redox potential, assessment of the antioxidative status in critically ill patients, improvement of the muscular performance of elderly persons, application of microarray-technology for the characterisation of effects of human growth hormone on blood mononuclear cells in healthy, active subjects, and influence of age, gender, and strength training on human muscle microRNA expression.


Hart, N., Sarga, L., Csende, Z., Koltai, E., Koch, L. G., Britton, S. L., et al. (2013). Resveratrol enhances exercise training responses in rats selectively bred for high running performance. Food Chem Toxicol.

Wessner, B., Gryadunov-Masutti, L., Tschan, H., Bachl, N., & Roth, E. (2010). Is there a role for microRNAs in exercise immunology? A synopsis of current literature and future developments. Exerc Immunol Rev, 16, 22-39.

Goldspink, G., Wessner, B., Tschan, H., & Bachl, N. (2010). Growth factors, muscle function, and doping. Endocrinol Metab Clin North Am, 39(1), 169-181, xi.

Wirtitsch, M., Roth, E., Bachleitner-Hofmann, T., Wessner, B., & Sturlan, S. (2009). Omega-3 and omega-6 polyunsaturated fatty acids enhance arsenic trioxide efficacy in arsenic trioxide-resistant leukemic and solid tumor cells. Oncol Res, 18(2-3), 83-94.

Strasser, E. M., Stattner, S., Karner, J., Klimpfinger, M., Freynhofer, M., Zaller, V., et al. (2009). Neuromuscular electrical stimulation reduces skeletal muscle protein degradation and stimulates insulin-like growth factors in an age- and current-dependent manner: a randomized, controlled clinical trial in major abdominal surgical patients. Ann Surg, 249(5), 738-743.

Petricevic, B., Wessner, B., Sachet, M., Vrbanec, D., Spittler, A., & Bergmann, M. (2009). CL097, a TLR7/8 ligand, inhibits TLR-4--dependent activation of IRAK-M and BCL-3 expression. Shock, 32(5), 484-490.

Bachl, N., Derman, W., Engebretsen, L., Goldspink, G., Kinzlbauer, M., Tschan, H., et al. (2009). Therapeutic use of growth factors in the musculoskeletal system in sports-related injuries. J Sports Med Phys Fitness, 49(4), 346-357.

Goldspink, G., Wessner, B., & Bachl, N. (2008). Growth factors, muscle function and doping. Curr Opin Pharmacol, 8(3), 352-357.

Bachl, N., Ruoff, G., Wessner, B., & Tschan, H. (2008). Electromagnetic interventions in musculoskeletal disorders. Clin Sports Med, 27(1), 87-105, viii.

Wirtitsch M, Wessner B, Spittler A, Roth E, Volk T, Bachmann L, Hiesmayr M. Effect of different lipid emulsions on the immunological function in humans: A systematic review with meta-analysis. Clin Nutr. 2007;26(3):302-13.
Wessner B, Strasser EM, Koitz N, Schmuckenschlager C, Unger-Manhart N, Roth E. Green tea polyphenol administration partly ameliorates chemotherapy-induced side effects in the small intestine of mice. J Nutr. 2007;137(3):634-40.

Wessner B, Strasser EM, Manhart N, Roth E. Supply of R-alpha-lipoic acid and glutamine to casein-fed mice influences the number of B lymphocytes and tissue glutathione levels during endotoxemia. Wien Klin Wochenschr. 2006;118(3-4):100-7.

Ploder M, Pelinka L, Schmuckenschlager C, Wessner B, Ankersmit HJ, Fuerst W, Redl H, Roth E, Spittler A. Lipopolysaccharide-induced tumor necrosis factor alpha production and not monocyte human leukocyte antigen-DR expression is correlated with survival in septic trauma patients. Shock. 2006;25(2):129-34.

Sadeghi K, Wessner B, Laggner U, Ploder M, Tamandl D, Friedl J, Zugel U, Steinmeyer A, Pollak A, Roth E, Boltz-Nitulescu G, Spittler A. Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns. Eur J Immunol. 2006;36(2):361-70.

Strasser EM, Wessner B, Manhart N, Roth E. The relationship between the anti-inflammatory effects of curcumin and cellular glutathione content in myelomonocytic cells. Biochem Pharmacol. 2005;70(4):552-9.

Roth E, Manhart N, Wessner B. Assessing the antioxidative status in critically ill patients. Curr Opin Clin Nutr Metab Care. 2004;7(2):161-8.

Wessner B, Strasser EM, Spittler A, Roth E. Effect of single and combined supply of glutamine, glycine, N-acetylcysteine, and R,S-alpha-lipoic acid on glutathione content of myelomonocytic cells. Clin Nutr. 2003;22(6):515-22.

Tamandl D, Bahrami M, Wessner B, Weigel G, Ploder M, Furst W, Roth E, Boltz-Nitulescu G, Spittler A.  Modulation of toll-like receptor 4 expression on human monocytes by tumor necrosis factor and interleukin-6: tumor necrosis factor evokes lipopolysaccharide hyporesponsiveness, whereas interleukin-6 enhances lipopolysaccharide activity. Shock. 2003;20(3):224-9.

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